Journal article

Phantom epistasis between unlinked loci

G Hemani, JE Powell, H Wang, K Shakhbazov, HJ Westra, T Esko, AK Henders, AF McRae, NG Martin, A Metspalu, L Franke, GW Montgomery, ME Goddard, G Gibson, J Yang, PM Visscher

Nature | Published : 2021

DOI: 10.1038/s41586-021-03765-z

University of Melbourne Researchers

Related Projects (2)

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The extent, causes and implications of pleiotropy among complex traits

The project seeks to understand how a DNA mutation can affect many characters or traits. Many traits are called complex because they are con..

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THE ROLE OF X-CHROMOSOME INACTIVATION IN QUANTITATIVE TRAIT VARIATION

This project aims to develop methods and software that can be applied to genetic and genomic studies in animal breeding, wildlife protection..

Grants

Awarded by Australian Research Council

Funding Acknowledgements

G.H. was funded by the Wellcome Trust and Royal Society (208806/Z/17/Z). J.E.P. is supported by National Health and Medical Research Council Fellowship (APP1175781). J.Y. and P.M.V. are supported by the Australian Research Council (DP160101343, DP160101056, FT180100186 and FL180100072) and the Australian National Health and Medical Research Council (1078037, 1078901, 1113400 and 1107258). J.Y. is supported by the Westlake Education Foundation. We are extremely grateful to all the families who took part in the ALSPAC study, the midwives for their help in recruiting them, and the whole ALSPAC team, which includes interviewers, computer and laboratory technicians, clerical workers, research scientists, volunteers, managers, receptionists and nurses.

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Keywords

Multidisciplinary Sciences
Explanation
Science & Technology
Science & Technology - Other Topics